AWL sentences

H-antigens into sugar chains of porcine gastric mucins, as revealed by lectin blotting and mass spectroscopy analysis of the sugars.

Oligosaccharides from CD43 and CD45 of CEM cells latently infected with HIV-1 were chemically analyzed.

Consistent with our previous results, we show that HIV-1 infection results in accumulation of exposed lactosamine residues, oligosaccharides recognized by galectin-1 on cell surface glycoproteins.

Fucα1-2 Gal linkages, or H-antigens, constitute histo-blood group antigens and are involved in various physiological processes.

It has been well established that Galectin-1 (GAL1), a β-galactoside-binding protein, regulates the viability of lymphoid cells.

The fraction of cells that died in response to galectin-1 exceeded the fraction of infected cells, indicating that death of uninfected cells occurred.

These antibodies, were initially produced in few individuals that acquired random mutations inactivating the corresponding genes and eliminating α-gal epitopes or Neu5Gc, which became nonself antigens.

Significantly, PP14 reacts with N-acetyllactosamine (LacNAc) as was also found for members of the galectin family, such as the potent immunoregulatory protein, galectin-1.

These antibodies further induced rapid, effective immune responses against virus antigens, thus preventing infections from reaching lethal stages.

This was demonstrated by preferential binding to fetuin as compared with its desialylated variant asialofetuin (ASF) and by using free α2,6- versus α2,3-sialylated forms of LacNAc in competitive inhibition and direct solid-phase binding assays.